Efficient Bayesian approach for multilocus association mapping including gene-gene interactions
نویسندگان
چکیده
منابع مشابه
Powerful multilocus tests of genetic association in the presence of gene-gene and gene-environment interactions.
In modern genetic epidemiology studies, the association between the disease and a genomic region, such as a candidate gene, is often investigated using multiple SNPs. We propose a multilocus test of genetic association that can account for genetic effects that might be modified by variants in other genes or by environmental factors. We consider use of the venerable and parsimonious Tukey's 1-de...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2010
ISSN: 1471-2105
DOI: 10.1186/1471-2105-11-443